Multiple sclerosis (MS) is characterised with exacerbations or progressing disability in young adults and related with several central nervous system sign and symptoms. Some psychiatric abnormalities, mostly depression, can be seen during the onset or progress of the disease. Our aim was ta evaluate the frequency of depression and anxiety and correlation between EDSS values with using the Beck Depression Scale (BDS) and Beck Anxiety Scale (BAS), among patients of our MS Clinic. Among the 23 patients; 17 patients were relapsing-remitting type MS patients (5 male and 12 female), 5 patients were secondary progressive type MS (2 male and 3 female), and one patient was primary progressive type MS. All patients were in remission peniod and they were not receiving either immunsuppressive or immune modulatuary therapy. Among 16 female, and 7 male patient, the mean age was 33.7 (23-50) and EDDS points were between 0-7. Mediumlhigh depression was found in 13 of 23 patients, and medium/high anxiety was found in 16 patients. No correlation was found between BDS/BAS values and EDDS scores. As there was no correlation between the disability levels of the patients and BDS, BAS values, and besides the diminished values of BDS and BAS values in some patients the cognitive assessment of the patients during the progression of depression, social stress, family living, atypical depression should be taken into account.